Our new Obvious+ tissue clearing system is the sole strategy that delipidates samples without improve in morphology and with minimal impact on structural integrity.
Megatome is actually a vibrating microtome intended to part a broad selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With high blade vibrating frequency and minimized blade deflection, Megatome enables large-throughput tissue sectioning with uniform surface area profile, and also small tissue hurt and information loss.
Antibodies may consider weeks to diffuse through only a few millimeters of tissue, having a steep labeling gradient from surface area to core.
Megatome is made for accuracy: the blade vibrates at a greater frequency and larger amplitude range than other microtomes, and features a unique deflection control system.
SE takes advantage of a rotational electric powered subject to disperse very electromobile molecules (such as antibodies or surfactant micelles) throughout a porous sample without the need of harming electrically billed constructions within the tissue. This enables two-four day clearing of intact organs,
Our preformulated EasyIndex Resolution raises and homogenize the refractive index of delipidated tissue samples, rendering them completely clear. This enables light penetration in to the sample and makes certain the acquisition of higher-resolution, in-concentration picture info.
Megatome is really a novel microtome which allows for prime-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimum tissue destruction and data loss.
It’s time to up grade your megatomi.com microtome to Megatome. With accurate high-frequency slicing for an unmatched range of sample dimensions and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied programs.
Totally delipidate total mouse brains or comparably sized samples in just one working day with SmartBatch+, or in one week with our passive clearing package.
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Leverage the Clear+ tissue clearing process, as well as eFLASH and patented stochastic electrotransport technologies, to fast crystal clear and label whole organs. Important highlights and functions include things like:
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